流感病毒具有种属特异性

构成流感病毒颗粒的蛋白质的不同，主要取决于流感病毒是在哪种生物中形成的。

病毒的组成对于其感染和传播能力是至关重要的。英国牛津大学的Edward Hutchinson，Ervin Fodor和他们的同事们，使用质谱仪识别并且量化了七种不同的流感病毒的蛋白质。这几种流感病毒是从哺乳动物的组织或者鸡蛋中获得的。作者还发现，这些蛋白具有共同的核心结构，但是一些元件具有宿主的独一无二性。

这个发现表明，鸡蛋或哺乳动物组织培养的流感疫苗在组织成分上存在不同。在相关的流感疫苗研制的过程中，我们需要密切注视这方面的差异。

原文：

The proteins that make up the influenza viral particle differ depending on which species the virus was generated in.

The composition of a virus is important for its ability to infect and spread. Edward Hutchinson, Ervin Fodor and their colleagues at the University of Oxford, UK, used mass spectrometry to identify and quantify the proteins in seven different flu viruses derived from either mammalian tissue or chicken eggs. The authors found a common core architecture of proteins, but some components were unique to the host.

The finding suggests that flu vaccines grown in chicken eggs or mammalian tissue could have different compositions.（转化医学网360zhyx.com）