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腾讯登录BJGP：年轻女性或经常忽视宫颈癌筛查的重要性
| 导读 | 近日，来自伦敦大学国王学院的研究人员通过研究表示，许多30岁以下的宫颈癌患者都是在首次出现疾病症状后超过3个月才被确诊为宫颈癌的，而很多时候患者自身并没有意识到疾病及症状的严重性，从而耽误了确诊时间和治疗，相关研究刊登于国际杂志British Journal of General Practice上。 |
近日，来自伦敦大学国王学院的研究人员通过研究表示，许多30岁以下的宫颈癌患者都是在首次出现疾病症状后超过3个月才被确诊为宫颈癌的，而很多时候患者自身并没有意识到疾病及症状的严重性，从而耽误了确诊时间和治疗，相关研究刊登于国际杂志British Journal of General Practice上。
134位女性中大约有1名会在其一生中的某个时间段患宫颈癌，宫颈癌是由人乳头瘤状病毒（HPV）引起的，HPV的感染非常常见，尤其是在年轻女性机体中，但是很多情况下感染并不会导致个体患宫颈癌，在英国，国家医疗服务系统通常会为25至64岁的女性进行筛查来预防宫颈癌的发生。这项研究中，研究人员对128名30岁以下的新近诊断为宫颈癌的个体进行研究，2010年英国30岁以下大约37%的女性都进行了诊断，而其中有40名个体出现了疾病症状去看医生才发现了宫颈癌，有86名个体是在进行正常医疗筛查时候发现的。研究者Lindsay Forbes表示，许多女性第一次去看医生后往往都会超过三个月才进行疾病的诊断，这就表明女性患者在出现宫颈癌症状后并没有立刻进行确诊治疗。
研究者建议，女性尤其是25岁以下的女性并不清楚宫颈癌的具体表现，因此需要即可看医生，而尽早就医会帮助患者进行早期诊断并且有效改善患者的生存质量，宫颈癌的筛查试验旨在帮助预防癌症的发生，出现持续性症状的女性需要进行一种全面合理性的检测而不光是简单的宫颈癌筛查。最后研究者Willie Hamilton表示，本文的研究目的在于帮助年轻女性提高宫颈癌筛查的意识，在个体出现症状时及早医治，对于有效控制病情非常重要。（转化医学网360zhyx.com）
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转化医学网推荐的原文摘要：
Delays in diagnosis of young females with symptomatic cervical cancer in England: an interview-based study
BJGP DOI: 10.3399/bjgp14X681757
Anita W Lim, Amanda J Ramirez, William Hamilton, Peter Sasieni, Julietta Patnick, Lindsay JL Forbes
Background Diagnosis may be delayed in young females with cervical cancer because of a failure to recognise symptoms.
Aim To examine the extent and determinants of delays in diagnosis of young females with symptomatic cervical cancer.
Design and setting A national descriptive study of time from symptoms to diagnosis of cervical cancer and risk factors for delay in diagnosis at all hospitals diagnosing cervical cancer in England.
Method One-hundred and twenty-eight patients <30 years with a recent diagnosis of cervical cancer were interviewed. Patient delay was defined as ≥3 months from symptom onset to first presentation and provider delay as ≥ 3 months from first presentation to diagnosis.
Results Forty (31%) patients had presented symptomatically: 11 (28%) delayed presentation. Patient delay was more common in patients <25 than patients aged 25–29 (40% versus 15%, P = 0.16). Vaginal discharge was more common among patients who delayed presentation than those who did not; many reported not recognising this as a possible cancer symptom. Provider delay was reported by 24/40 (60%); in some no report was found in primary care records of a visual inspection of the cervix and some did not re-attend after the first presentation for several months. Gynaecological symptoms were common (84%) among patients who presented via screening.
Conclusions Young females with cervical cancer frequently delay presentation, and not recognising symptoms as serious may increase the risk of delay. Delay in diagnosis after first presentation is also common. There is some evidence that UK guidelines for managing young females with abnormal bleeding are not being followed.
BJGP DOI: 10.3399/bjgp14X681757
Anita W Lim, Amanda J Ramirez, William Hamilton, Peter Sasieni, Julietta Patnick, Lindsay JL Forbes
Background Diagnosis may be delayed in young females with cervical cancer because of a failure to recognise symptoms.
Aim To examine the extent and determinants of delays in diagnosis of young females with symptomatic cervical cancer.
Design and setting A national descriptive study of time from symptoms to diagnosis of cervical cancer and risk factors for delay in diagnosis at all hospitals diagnosing cervical cancer in England.
Method One-hundred and twenty-eight patients <30 years with a recent diagnosis of cervical cancer were interviewed. Patient delay was defined as ≥3 months from symptom onset to first presentation and provider delay as ≥ 3 months from first presentation to diagnosis.
Results Forty (31%) patients had presented symptomatically: 11 (28%) delayed presentation. Patient delay was more common in patients <25 than patients aged 25–29 (40% versus 15%, P = 0.16). Vaginal discharge was more common among patients who delayed presentation than those who did not; many reported not recognising this as a possible cancer symptom. Provider delay was reported by 24/40 (60%); in some no report was found in primary care records of a visual inspection of the cervix and some did not re-attend after the first presentation for several months. Gynaecological symptoms were common (84%) among patients who presented via screening.
Conclusions Young females with cervical cancer frequently delay presentation, and not recognising symptoms as serious may increase the risk of delay. Delay in diagnosis after first presentation is also common. There is some evidence that UK guidelines for managing young females with abnormal bleeding are not being followed.
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