NIH出资1400万美元用于建立新型生物样本库

  Coriell研究所日前宣布，他们已经接受了来自美国国立卫生研究院1400万美元的竞争性资助，而这些资助是用来用来支持国立医学科学研究所(NIGMS)进行人类基因细胞库研究的。

  来自NIGMS 的5年资助将会大大支持生物样本库的建设，该生物样本库包括了超过11300个细胞系及能展现890种疾病状态的5700份DNA样本，也包括几个不同人群的染色体异常情况，另外该生物样本库还包含了健康个体的样本及40份诱导的多能干细胞系。

  Coriell研究所的主任兼CEO Michael Christman表示，快速、高效及廉价DNA测序技术的出现将会为我们迎来一个激动人心的基因组时代，而此时的生物样本库也比以往任何时候都要更加重要。

  含有高质量、具有特征性的生物样本库可以帮助科学家更好地揭示人类疾病的发病机理，而大量资源的收集也将助力科学家们对罕见的遗传性疾病进行解读，就比如早衰和杜氏肌萎缩症，以及其它的障碍，如代谢性疾病和遗传性癌症等。

  去年位于新泽西州的一家生物医学研究中心就在加州的诺瓦托市建立了一个西海岸生物样本库。（转化医学网360zhyx.com）

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The Coriell Institute today announced that it has received a $14 million competitive grant from the National Institutes of Health to support the National Institute of General Medical Sciences (NIGMS) Human Genetic Cell Repository.

The five year grant from NIGMS will support a biobank which includes more than 11,300 cell lines and 5,700 DNA samples representing 890 disease states and chromosomal abnormalities in several distinct human populations. It also contains healthy control samples and 40 induced pluripotent stem cell lines.

"The advent of faster, better, and cheaper DNA sequencing is ushering in an exciting genomic era in which biobanks are more essential than ever before," Coriell Institute President and CEO Michael Christman said in a statement. "Biobanks with high-quality, characterized specimens are helping scientists better understand many human diseases. This collection is a powerful resource for scientists studying rare genetic diseases, like progeria and Duchenne muscular dystrophy, as well as other disorders such as metabolic diseases and hereditary cancers."

Last year, the Camden, NJ-based biomedical research center launched a West Coast biobank in Novato, Calif.