NEB, Benchling合作开发DNA组装工具

  新英格兰生物实验室公司(NEB)与生物器械生产商Benchling近日宣布合作，简化Golden Gate组装工具在克隆实验中的设计与应用。

  两家公司正在推出一个免费的在线工具,该工具将作为Benchling分子生物学应用程序与NEBGolden Gate组装工具的一部分,用于组装DNA片段。

  NEB与Benchling所推出的在线工具将为使用者量身定做Golden Gate反应，从而最小化实验过程中引物和基因重叠区错误设计的几率。在研究人员向该工具中输入其目的结合片段的同时，该工具变会自动进行反应模拟与引物设计，生成目的基因的最终的构造。研究人员可以对该项工具的实验设计进行调整，导出实验结果以及下载实验流程。

  Benchling合伙人和CEOSajith Wickramasekara在声明中表示：“我们的新型实验设计工具不会仅仅局限于帮助生物学家模拟Golden Gate组装实验，我们将为传统克隆实验领域引入一项更加高效的实验体系。”

  金融和其他合作细则尚未披露。（转化医学网360zhyx.com）

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New England Biolabs and Benchling today said they are collaborating to simplify the design of cloning experiments using the Golden Gate Assembly method.

The firms are launching a free online tool that will be available as part of Benchling's molecular biology app and as part of the NEB Golden Gate Assembly tool, which is used for assembling DNA fragments.

NEB and Benchling's tool designs the Golden Gate reaction for the user, thereby minimizing the risk of incorrectly designed primers and overlaps, they said. Researchers input the DNA fragments they want to combine and the tool simulates the reaction, designs the primers, and generates the final construct. The researchers can adjust the design, export the results, and download a protocol.

"We wanted to develop a tool that helps not just biologists currently working with the Golden Gate Assembly method, but also those who are using conventional cloning methods and looking to make the leap to a more powerful system," Benchling Co-founder and CEO Sajith Wickramasekara said in a statement.

Financial and other terms of the deal were not disclosed.