Allele建立iPSC样本库商业公司

  Allele生物技术及制药公司今日宣布，他们已经建立了一家以人类诱导多能干细胞（iPSC）样本库为基础的商业公司。
  该公司位于美国圣地亚哥，他们表示，除了为客户提供服务以外，这个iPSC样本库或将作为一个资源库来供生物医药研究者进行相关科学研究；在得到客户同意的前提下，成千上百种iPSC细胞系，以及序列数据库和健康信息都提供给科学家和临床医生。
  目前Allele公司已经在总部附近获得了一块1.8万平方英尺的地皮，并且计划建立iPSC样本库，该样本库的建立或将作为人类iPSCs的cGMP产生的中心，为合成mRNA平台的公司提供便利，这项技术将可以在不对外源DNA进行随机整合或利用病毒的条件下产生所需的目的细胞。
  Allele公司已经建立了科学顾问委员会，用来指导iPSC样本库商业公司的业务，Mahendra Rao 和Joseph Paulauskis目前为该委员会的第一成员，Rao是 Invitrogen公司再生医学部的副总裁，同时也是美国国立卫生研究院的再生医学中心的创会理事，目前他是Q Therapeutics公司的首席战略官。
  Paulauskis 是Paradigm Dx公司的首席运营官，也是国际基因组协会的副总裁。（转化医学网360zhyx.com）
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转化医学网推荐的原文摘要：

Allele Establishes iPSC Bank Business
Allele Biotechnology & Pharmaceuticals today announced it has formed a commercial business to bank human induced pluripotent stem cells by private individuals. 

The San Diego-based firm said that in addition to providing a service to its customers, the iPSC bank will be a resource to biomedical researchers. With consent given by the bank's customers, thousands of iPSC lines — along with accompanying sequence database and health information — will be made available to scientists and clinicians. 

Allele has acquired an 18,000-square-foot facility near its headquarters in preparation of establishing the iPSC bank, which will serve as the center of cGMP production of human iPSCs using the firm's synthetic mRNA platform. The technology generates cells without the random integration of foreign DNA or the use of viruses or virus-based elements, it said. 

The firm has also established a scientific advisory board to guide the iPSC bank business. Mahendra Rao and Joseph Paulauskis are the board's first members. Rao was the vice president of regenerative medicine at Invitrogen and the founding director of the National Institutes of Health's Center for Regenerative Medicine. He is currently chief strategy officer at Q Therapeutics. 

Paulauskis is the chief operating officer at Paradigm Dx and the VP of research and biobanking for the International Genomics Consortium.